GET Journal of Biosecurity and One Health

GET Journal of Biosecurity and One Health (2023)

Identification of the Requirements and Expectations of Interested Parties in a Biobank in Sub-Saharan Africa

Authors: Diané KM,2*, Money M1,2 Bouagnon JJR1,2, Cissé S1,2, Aka KAE1,2, Kintossou KA1,2, Coulibaly L1,2, N’Guessan F1,2, Setchi LO3, and Dosso M4

GET Journal of Biosecurity and One Health, Volume 2, Issue 2, (2023)

Article Keywords: Stakeholders; Biobank; Sub-Saharan Africa; Knowledge; Needs and Expectations


Journal Volume & Issue

Volume 2, Issue 2


Volume 1, No. 4, 2022

Pages 34-40

Ebola Survivors are not at Increased Risk for Gynecologic Surgeries

Gorpudolo-Dennis N1; Kennedy SB2*; Reilly C3 and Sankoh M1

1Department of Obstetrics and Gynecology, Redemption Hospital, New Kru Town, Montserrado County, Monrovia, Liberia.

2UL-PIRE Africa Center, An Infectious Disease Research Center, Ground Floor, Graduate School Building, University of Liberia, Monrovia, Liberia.

3Department of Biostatistics, University of Minnesota, Minneapolis, Minnesota, USA.

*Corresponding Author: Stephen B. Kennedy, MD, MPH, UL-PIRE Africa Center, An Infectious Disease Research Center
Ground Floor, Graduate School Building, University of Liberia, Monrovia, Liberia. Tel: +231 770 645 830

Orchid No:


As the result of multiple signs and symptoms, and complications observed among survivors of the Ebola virus disease (EVD), there is an assumption that survivors might experience perturbations within their clotting parameters. This may eventually lead to increased bleeding time, predisposing them to increased risk for surgical complications. This study aimed to comparatively review specific intra-operative parameters such as uterine fibroids and polyps among a number of EVD survivors and non survivors undergoing elective gynecologic surgeries at Redemption Hospital, a tertiary specialized referral hospital located within one of the EVD hotspots, in Liberia from January to October 2016. A case-control study was conducted wherein cases were referred from the Partnership for Research on Vaccines and Infectious Diseases in Liberia (PREVAIL), an EVD clinical trial platform, while controls were sampled from the general patient population, at Redemption Hospital. The controls were matched based on age, employment status and parity. All surgeries were performed by single surgeon based on a surgical checklist that included designated intra- and post-operative parameters. Statistical analysis such as counts, percentiles, confidence intervals and relative risks were performed to assess the differences between the cases and controls, respectively. Survivors were between the ages of 42 years and 44 years for controls with an average interval between discharge from the Ebola Treatment Unit (ETU) and surgical intervention of greater than one year. The median duration of surgical procedure was 60 minutes and blood loss of 250 ml in both groups. Besides the relative risks (RR) of receiving antibiotics for more than 3 days of 1.5 (85.7% vs. 57.1%) and hospitalization of more than 7 days of 0.25 (14% vs. 57%) for survivors as compared to controls, most of the indicators were not significantly different. The findings revealed that EVD survivors who present with benign tumors such as uterine fibroids, polyps, or adenomyosis, requiring elective uterine surgery such as myomectomy and/or hysterectomy are generally not at increased risk of surgical complications because most of the indicators (hospitalization, blood loss, antibiotics, etc.) were not significantly different between the two groups. Findings from this study may potentially revise the approaches used by gynecologists and general surgeons during encounters and/or interventions with patient(s) concerning emerging infectious diseases (EIDs).

Keywords: Ebola Virus Disease (EVD), Emerging Infectious Diseases (EIDs), Ebola Survivors, Uterine Surgery, Females, Liberia


Biobanks are important infrastructures facilitating biomedical research. It is recognized that improving the
health of individuals and populations increasingly requires the use of large-scale collections of human
biological samples and associated data. In this regard, biobanks are a valuable resource to facilitate effective research. The objective of this study was to identify the current and future needs and requirements of our stakeholders, so that measures to satisfy them could be put in place. An exploratory, quantitative and qualitative study was carried out by means of an anonymous survey, on the expectations and requirements of the stakeholders of biobank. This descriptive cross-sectional study which took place over 3 weeks in 2021. Fifty (50) participants working in Abidjan and in the interior of the country agreed to answer the anonymous survey. Among them, 32 (64.0%) were men. The professions of research biologists represented 19 (38.0%) physician-pharmacist practitioners 11 (22.0%). The overall expectations of stakeholders in relation to operational processes were: compliance with regulations, standards and best practices 42 (84.0%); feedback on uses 40(80.0%); staff safety 40(80.0%); information on the possible use of biological resources 38(76.0%). The administrative authorities who took part in the survey unanimously identified practically all the expectations relating to biobank management processes as important. The
following essential expectations were identified: acquiring the necessary skills, internal communication concerning quality and operations, performance/efficiency of support activities, satisfaction of interested parties, 100% staff safety. For the development of biobanks for research purposes, political decision-makers, regulators and researchers should take into account the opinions of all social sectors, in particular the general public.